Docetaxel mushonga unoshandiswa nevakawanda kurapa magomarara akasiyana siyana, unoshanda nekukanganisa ma microtubule mumasero egomarara. Hunhu uhu hunoita kuti docetaxel ive chombo chine simba mukurapa bundu, kunyanya kana dzimwe nzira dzekurapa dzisingashande.
I.Mechanism of Action:Kupindira neMicrotubules muCancer Cells
Docetaxelndeye taxane class ye chemotherapeutic agents, iyo inoshanda nekukanganisa zvimiro zvemicrotubule mumasero, nekudaro zvichikanganisa kupatsanurwa kwesero.Mamicrotubules akakosha maumbirwo mukati memasero anoita basa rakakosha mukukamura maseru, anobatsira sero kupatsanurwa kuita masero matsva maviri.Docetaxel inovhiringa basa rakajairwa reaya mamicrotubules, anogona kudzivirira kana kunonoka kukura uye kupararira kwekenza maseru.
II.Kurapa Makonzo Akawanda
Gomarara rezamu:Docetaxel inoita basa rakakosha mukurapwa kenza yemazamu,kunyanya kana cancer yapararira kune dzimwe nzvimbo (mumatanho epamusoro) uye dzimwe nzira dzekurapa dzatadza kupa mhedzisiro inogutsa.Inogona kubatsira kudzora kufambira mberi kwegomarara rezamu.
Non-Small Cell Lung Cancer (NSCLC):NSCLC ndeimwe yemhando dzakawanda dzekenza yemapapu, uye docetaxel inowanzoshandiswa pamwe chete nemamwe madhiragi echemotherapy kurapa zviitiko zvakakura kana kuti kenza yapararira kune dzimwe nzvimbo. kusanganisa kurapwa kunogona kubatsira kunonoka kukura kwemamota.
Prostate Cancer:Docetaxel inowanzoshandiswa mukurapa kenza yeprostate,kunyanya apo kenza yasvika padanho repamusoro kana dzimwe nzira dzokurapa dzapera.Kusanganiswa kwayo nemimwe mishonga kunogona kuvandudza mikana yekubudirira kurapwa.
Gomarara reGastric (Gomarara remudumbu):Docetaxelinoshandiswawo mukurapa gomarara remudumbu, kunyanya kune mamwe marudzi chaiwo egomarara remudumbu.Inowanzosanganiswa nemimwe mishonga kuti ipe kurapa kwakadzama.
Muchidimbu,docetaxel, chemotherapy drug iyo inhibits cell division nekupindira ne microtubule zvivako mumasero emukenza, yakaratidza kushanda kwakakosha mukurapa kwemarudzi akawanda ekenza.Zvisinei, inogonawo kufambidzana nehuwandu hwemigumisiro, saka inofanira kushandiswa pasi pe kutariswa kwevashandi vekurapa kuti ive nechokwadi chekurapa kwakakwana uye kuchengetedzwa kwemurwere.
Ongorora: Iko kugona kushanda uye mashandisirwo ataurwa muchinyorwa chino anotorwa kubva kumabhuku akaburitswa pachena.
Yakawedzera Kuverenga: Yunnan Hande Biotech Co., Ltd. yakatarisana nekugadzirwa kwedocetaxel zviwanikwa kweanopfuura makore makumi maviri, uye ndiye ega akazvimirira anogadzira echirimwa-inotorwa anticancer drug docetaxel raw materials yakatenderwa nemasangano anodzora akadai seUS FDA, European EDQM, Australian TGA, Chinese CFDA, India, uye Japan.
Nguva yekutumira: Oct-26-2023