Artemisinin 99% Artemisia annua inobvisa mishonga yemishonga

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Artemisinin mushonga une simba rakanaka mukurapa marariya.Iyo sesquiterpene lactone ine peroxide boka rinotorwa kubva kuArtemisia annua.Iine maitiro ekushanda kwepamusoro, kukurumidza kushanda, kubvisa kupisa uye kubvisa kupisa kwezhizha, kuderedza kushomeka kwekupisa, kuuraya protozoa uye kuderera kwehuturu.Parizvino, kushanda kweartemisinin based combined therapy (ACT) yekurapa marariya kwasvika kudarika 90% pasi rose.Yakave ichishandiswa zvakanyanya mukurapa marariya pasi rose.
1, Basa
1. Anti malaria
Malaria (inowanzozivikanwa se pendulum cold and fever disease) chirwere chinotapukira chezvipembenene.Ichi chirwere chinotapukira chinokonzerwa nekurumwa kwemuviri wemunhu nePlasmodium.Inogona kuoneka hepatosplenomegaly uye anemia mushure mekudzokorora kurwiswa kwenguva yakareba.Artemisinin yakabatsira mukurapwa kwemarariya kusvika pamwero wakati.Iyo peroxide bond muchimiro che artemisinin ioxidizing uye iboka rakakosha pakuramba marariya.Nzira yekuita ndeyekuti boka rakasununguka rinogadzirwa neartemisinin mu vivo rinosunga kuPlasmodium falciparum protein uye rinoshandura sero membrane chimiro chePlasmodium falciparum.Mushure memahara radicals asangana nePlasmodium protein, iyo bilayer membrane ye mitochondria ichazvimba nekutsemuka, uye pakupedzisira inodonha, zvichikonzera kuparadzwa kwesero chimiro uye basa rePlasmodium, uye iyo chromatin munucleus ichakanganiswawo kune vamwe. extent.
2. Antitumor
Malignant bundu ndiyo mhondi yekutanga kuisa hutano hwevanhu pangozi.Kana ikasarapwa nenguva, inoisa pangozi kuchengeteka kwehupenyu.In vitro kuyedza kwakaratidza kuti imwe dosi ye artemisinin inogona kukonzeresa apoptosis yemhando dzakawanda dzekenza maseru, senge hepatoma masero, masero egomarara rezamu, maseru egomarara remuchibereko uye zvichingodaro, uye zvakanyanya kutadzisa kukura kwekenza maseru.Inowanikwa kuti artemisinin inogona kugadzirisa kutaura kwecyclin mumasero emamota, kuwedzera mhedzisiro yeCKIs uye kutungamirira kune bundu cell cycle kusungwa;Kana kutungamira kune apoptosis uye inhibit tumor angiogenesis kuramba kuitika uye kukura kwebundu.Artemisinin inoshandiswa kurapa leukemia nekuita pane sero membrane yeleukemia masero, ichiwedzera permeability ye membrane uye kushandura osmotic pressure, zvichikonzera kuwedzera kwecalcium concentration mumasero, kuitira kuti activate calpain, kuita kuti sero membrane rizvimbe. uye kutsemuka, mhanyisa kuburitswa kweapoptotic zvinhu uye kuwedzera kumhanya kweapoptosis.
3. Kurapa kwepulmonary hypertension
Pulmonary hypertension (PAH) inzvimbo yepathophysiological inoratidzwa nepulmonary artery remodeling uye kukwira kwepulmonary artery pressure kune imwe muganhu.Inogona kuva complication kana syndrome.Artemisinin inoshandiswa kurapa pulmonary hypertension: inogona kuderedza pulmonary artery pressure uye kuvandudza zviratidzo kune varwere vane PAH nekuzorodza tsinga dzeropa.Zaiman et al.Yakaonekwa kuti artemisinin ine anti-inflammatory effect.Artemisinin uye zvinhu zvayo zvakakosha zvinogona kudzivisa zvinhu zvakasiyana-siyana zvinopisa, uye zvinogonawo kudzivisa kugadzirwa kwe nitric oxide nevamiririri vanopisa;Artemisinin ine immunomodulatory effect;Feng Yibai nevamwe vakawana kuti artemisinin inogona kudzivisa kupararira kwevascular endothelial masero uye vascular smooth muscle masero, uye zvino inoita basa rinokosha mukurapa kwePAH;Artemisinin inogona kudzivisa basa rematrix metalloproteinases, nokudaro kudzivisa pulmonary vascular remodeling;Artemisinin inogona kutadzisa kutaura kwePAH ine chekuita nemacytokines uye kuwedzera kuwedzera anti vascular remodeling effect ye artemisinin.
4. Kudzorwa kwezvirwere zvemuviri
Zvinoonekwa kuti kuyerwa kweartemisinin uye zvinobva mairi zvinogona kuvharidzira zviri nani T lymphocyte mitogen uye kukurudzira kuwanda kwembeva spleen lymphocytes pasina cytotoxicity.Ichi chiwanikwa chine kukosha kwakanaka kwekurapa kweT lymphocyte mediated autoimmune zvirwere.Artemisia annua girazi vhiniga inogona kukwidziridza isingatarisirwi uye inonatsiridza iyo yakazara inozadzisa chiitiko chembeva serum.Dihydroartemisinin inogona kurambidza zvakananga kupararira kweB lymphocytes, kuderedza kubudiswa kweautoantibodies neB lymphocytes, kuderedza humoral immune immune, inhibit humoral immune uye kuderedza kuumbwa kwezvirwere zvemuviri.
5. Antifungal
Iyo antifungal mhedzisiro yeartemisinin inoitawo kuti artemisinin iratidze imwe antibacterial chiitiko.Tsvakurudzo yakasimbisa kuti zvakasara zvehupfu uye decoction yemvura ye artemisinin yakanga ine antibacterial effect pa anthrax, Staphylococcus epidermidis, catarrhalis uye diphtheria, uye yakanga ine mamwe antibacterial migumisiro yechirwere chetachiona, Pseudomonas aeruginosa, Staphylococcus aureus uye dysentery bacilli.
2. Nzvimbo yekushandisa
Artemisia annua inoshandiswa semushonga unorwisa marariya.Kushandiswa kwaro kuchipatara kwakaratidza kuti artemisinin nezvinobuda pairi zvine mhedzisiro yakakosha paPlasmodium falciparum uye Plasmodium falciparum, kunyanya Artemisia annua a, ine simba rakasimba kupfuura mamwe mishonga yeartemisinin pakuuraya intracellular clones yePlasmodium falciparum.

Product Parameters

COMPANY PROFILE
Product Name	Artemisinin
CAS	63968-64-9
Chemical Formula	C15H22O5
Brand	Huye
Manufacturer	YUnnan Hande Bio-Tech Co., Ltd.
Ckubuda	Kunming,China
Established	1993
BASIC ZVINO
Mashoko anoreva zvakafanana	3,12-epoxy-12h-pyranol(4,3-j)-1,2-benzodioxepin-10(3h)-imwe,octahydro-3,6,9-tri;artemisiaannual.,extract;huanghuahaosu;octahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano(4,3-j) -1,2-benzodioxepin-10(;qinghausau;qinghausu; QHS; ARTEMISIN99%
Chimiro
Kurema	282.34
HS Code	N/A
HunhuSpecification	Kutsanangurwa kwekambani
Certificates	N/A
Assay	Customized maererano nezvinodiwa nevatengi
Chitarisiko	Asina mavara acicular crystal
Nzira Yokuchera	Artemisia annua
Kugona Kwegore	Customized maererano nezvinodiwa nevatengi
Package	Customized maererano nezvinodiwa nevatengi
Test Method	N/A
Logistics	Multipletransports
PaymentTerms	T/T, D/P, D/A
Oipapo	Gamuchira kuongororwa kwevatengi nguva dzese;Batsira vatengi nekunyoresa kunyoresa.

1.Zvigadzirwa zvese zvinotengeswa nekambani ndezve semi-yakapera mbishi zvinhu.Zvigadzirwa zvinonyanya kunangana nevagadziri vane magwaro ekugadzira, uye zvigadzirwa hazvisi zvigadzirwa zvekupedzisira.
2.Iyo inogona kushanda uye zvikumbiro zvinobatanidzwa mukusuma zvose zvinobva mumabhuku akabudiswa.Vanhu havakurudzire kushandiswa kwakananga, uye kutenga kwega kunorambwa.
3.Mapikicha uye ruzivo rwechigadzirwa pawebhusaiti ino ndezvekutarisa chete, uye chigadzirwa chaicho chichakunda.