Paclitaxel inorwisa sei cancer?

Paclitaxel is diterpenoid yakatorwa kubva kuTaxus genus Taxus, uye masayendisiti akawana kuti ine yakasimba antitumor chiitiko mukuongorora kuyedza.Parizvino,paclitaxelinoshandiswa zvakanyanya mukurapa kenza yemazamu, kenza yeovarian, isiri-diki kenza yemapapu, kenza yepancreatic, kenza yesophageal, kenza yemudumbu, musoro nemutsipa bundu, nyoro nyoro sarcoma uye mamwe mamota akashata, uye ndeimwe yeanowanzo akashandisa chemotherapy mishonga mumakiriniki maitiro.Saka paclitaxel inorwisa cancer sei chaizvo?Ngatitarisei pazasi.

Paclitaxel inorwisa sei cancer?Zvinonyatsozivikanwa kuti panguva yekuparadzaniswa kwesero, sero rakakamurwa kuita zvikamu zviviri.Mushure mekunge chromosome yadzokororwa, iyo spindle filament inoidhonza kubva panzvimbo yayo yepakutanga kuenda kumativi ese, uye spindle inoda depolymerization ye microtubules se cytoskeleton kuti iumbe, maChromosomes anogona chete kupedzisa mitosis nekuenda kumatanda pasi pekukweva kwechirukwa uye. iyo spindle filament, saka ma microtubules akakosha zvikuru mukukamukana kwesero.

Muna 1979, chiremba wemishonga Horwitz akawana izvozvopaclitaxelinogona kusunga ku tubulin uye kukurudzira polymerization ye tubulin kuti iite microtubules, nokudaro ichidzivisa yakajairika physiological disaggregation ye microtubules, zvichiita kuti isakwanisa kuumba spindles uye spindle filaments, zvichiita masero Kusakwanisa kupatsanura kazhinji kunodzivirira kukurumidza kubereka kwekenza masero uye induces apoptosis. yekenza masero.Naizvozvo, pakati pemishonga inorwisa cancer, paclitaxel inoonekwa se microtubule inhibitor mu mitosis.

Ongorora: Iko kugona kushanda uye mashandisirwo anotsanangurwa muchinyorwa chino anotorwa kubva kumabhuku akaburitswa.

Kuwedzera kuverenga:Yunnan Hande Biotechnology Co., Ltd yanga yakatarisana nekugadzirwa kwepaclitaxel kwemakore makumi maviri nemasere.Ndiyo yekutanga yakazvimirira kugadzira pasi rose-yakagadzirwa anticancer drug paclitaxel iyo yakatenderwa neUS FDA, European EDQM, Australian TGA, China CFDA, India, Japan nemamwe masangano anodzora nyika.enterprise.Kana uchida kutengaPurogiramu inonzi Paclitaxel,ndapota taura nesu online.