Yew taxus chinensis inotorwa inotorwa kubva muzvinomera zvinoshomeka, yakaradzikwa, hunde, ganda, mudzi une zvinhu zvikuru zvinongedzo ndezvi:yew alkali diterpenoid compounds,yew ning A uye yew,yew ning H,yew,yew ning K,l,yew alkali, jinsong yellow ketone, mutsetse unosiya A,iyi inosiya ketone ketone,jinsong double yellow ketone,naphtha,yew,polysaccharide,tannins,tanned red,etc.,inogonawo kuva nemamwe mapolyphenols,amino acids,huni resin,inorganic elements.Paclitaxel ine anti-leukemia uye bundu mhedzisiro.
Paclitaxel, yatichataura nezvayo, ndiyo yakanyanya kunaka yekurwisa cancer yakawanikwa kusvika parizvino. Yakashandiswa zvakanyanya mukurapa kenza yemazamu, kenza yeovarian, kenza yemusoro nemutsipa, kenza yemapapu nezvimwe zvakawanda. mamwe kenza kuchipatara.
Natural Paclitaxel vs Semi-synthetic Paclitaxel
Kusachena:
Natural paclitaxelinotorwa kubva kumidzi, madzinde nemashizha eTaxus chinensis.After column chromatography and recrystallization, the whole process is physical extraction and purification without chemical reaction.Itsvina irimo inobva kune zvinoumba chirimwa pachacho,uye hapana tsvina. zvinounzwa nemakemikari synthesis.Saka, kusachena kwekugadzirisa kwepaclitaxel yepanyama kunonyanya kudzidzwa uye kunowedzera kudzoreka panguva ino.
Semi-synthetic paclitaxeline makemikari akawanda kupfuura echisikigo mukuita kwayo, uye kusvibiswa kwayo kwakawanda kupfuura kwechisikigo, kusanganisira imwe yakatorwa kubva muzvirimwa, uye kumwe kusvibiswa kunobva mumakemikari synthesis reaction. Muchiitiko ichi, huwandu nemhando yetsvina inogara ichichinja. Naizvozvo, semi-synthetic paclitaxel ine yakaderera controllability mutsvina, uye tsvina itsva inoda kugara ichidzidzwa mukugadzira. zvakasiyana kwazvo, uye kuongororwa kwakananga kunodiwa.
Yunnan Hande Bio-Tech yave ichiita basa rekuchera nekusimudzira mitero kwemakore makumi matatu, uye zvigadzirwa zvayo zvakakosha.natural paclitaxel,10-DAB semi-synthetic paclitaxel,10-deacetylbaccatin III,docetaxel,cabazitaxel,etc.For more information about paclitaxel APIs,please contact us!!!(Whatsapp/Wechat:+86 18187887160)
Nguva yekutumira: Jan-19-2023