Paclitaxel chigadzirwa chechisikigo chakatsaurwa uye chakacheneswa kubva pamakwati, midzi yehuni, mashizha, nhungirwa nembeu dzemuti redbud, ine yakanyanya kunaka mumakwati.Paclitaxelinonyanya kushandiswa kugomarara reovarian nemazamu, asi inoshandawo kugomarara remapapu, colorectal cancer, melanoma,gomarara remusoro nemutsipa, lymphoma uye bundu remuuropi.Ngatitarisei paclitaxel natural anti-cancer drug munyaya inotevera.
Paclitaxel inoshandiswa zvakanyanya mukurapa kenza yemapapu, kenza yemazamu, kenza yeovarian, kenza yemusoro nemutsipa, kenza yemudumbu uye mamwe mamota akashata. Inogona kugadzira microtubulin uye microtubulin dimer, inoumba microtubules, kurasikirwa nesimba, kukurudzira uye kukurudzira microtubulin polymerization. , microtubule musangano uye kudzivirira depolymerization, nokudaro kudzikamisa microtubules uye inhibiting mitosis uye kukonzeresa apoptosis yekenza masero, nokudaro zvinomisa kumisa kuwanda kwekenza maseru uye kutamba basa rinopesana nekenza.
Patova nemakore anoda kusvika 30 kubvira ipapopaclitaxelyakatengeswa muna 1992.Nekuda kwekuita kwayo chaiko, kuratidzwa kwakakura uye kudiwa kukuru kwekiriniki, kutsvagisa nekuvandudzwa kwemhando dzepimo yepaclitaxel yaenderera mberi, uye mafomu epaclitaxel dosage akatengeswa anosanganisira akajairwa jekiseni repaclitaxel,paclitaxelLiposome uye albumin paclitaxel.Zvigadzirwa zvepaclitaxel pari zvino ndizvo zviri pamusoro-soro chemakemikari vamiririri muChina maererano nehuwandu hwekutengesa, uye zvakare yakakura maererano nehuwandu hwekutengesa mumunda we antitumor zvinodhaka.
Ongorora: Iko kugona kushanda uye mashandisirwo anotsanangurwa muchinyorwa chino anobva kumabhuku akadhindwa.
Nguva yekutumira: Jun-13-2023