Paclitaxel, seyekutanga chemotherapy mushonga wakatorwa kubva mumiti yechisikigo, ichiri imwe yemishonga yakajairika mubundu chemotherapy kusvika nhasi.Paclitaxelmushonga wechisikigo unorwisa bundu wakatorwa kubva mumiti ye taxus, uye maitiro ayo ekuita kusimudzira microtubule aggregation kuti inhibit tumor cell mitosis.Ndiyo imwe yeakanakisa echisikigo anti-bundu mishonga mumusika wemishonga, uye pane kudiwa kukuru. mumusika wepasi rose wemishonga.Paclitaxel yakakamurwa kuita natural paclitaxel uye semi synthetic paclitaxel.Ngatitarisei basa re10-Dab Semi-Synthetic Paclitaxel mugwaro rinotevera.
10-Dab Semi-Synthetic Paclitaxelis a semi synthetic paclitaxel derivative with pharmacological activities like natural paclitaxel.Paclitaxe is an effective anti-cancer drug,inogona kushandiswa kurapa marudzi akasiyana egomarara,segomarara rezamu,ovarian cancer,kenza yemapapu negomarara remudumbu.The preparation ye precursor 10-DAB ye paclitaxel kuburikidza ne semi synthetic nzira inogona kuwedzera goho uye kuchena kwe paclitaxel, kuderedza mutengo wekugadzira, uye kuita kuti paclitaxel ive yakasimba uye ine hupfumi. Pamusoro pezvo, 10-DAB pachayo inewo zvimwe zviitiko zvemishonga, senge inhibitory mhedzisiro. pane mamwe masero emamota.
10-Dab Semi-Synthetic Paclitaxelinogona kuita mabasa mazhinji nemhedzisiro, kwete chete sechigadzirwa chepakati chemushonga, asiwo seyakagadzirwa chigadzirwa chemushonga.Kubva pachitarisiko, inoratidzika sekristaro chena.Ndiyo inonyanya kushandiswa muindasitiri yemishonga uye inogona kuva inoshandiswa seyakagadziriswa mushonga, iyo ine simba rakanaka pakugadzira yakakura-spectrum antiviral mishonga.
Nguva yekutumira: Jun-01-2023