Isu tinoziva kuti marudzi epaclitaxel akatengeswa anosanganisira paclitaxel jekiseni, liposomal paclitaxel, docetaxel, uye albumin-bound paclitaxel.Ndezvipi zvakanakira iyo ichangobva kutengeswa paclitaxel uye paclitaxel polymer micelles?Ngatitarisei zvinotevera.
Zvakanakira paclitaxel polymer micelles
1. Iyo copolymer inozvibatanidza mumvura kuti iite nanocarrier ine "core-shell" chimiro.Iyo nyukireya yakavharidzirwa paclitaxel ye micelle haina kuderedzwa, kuitira kuti inogona kuita basa muropa kwenguva yakareba.
2. Iyo polymer micellar paclitaxel particles idiki kwazvo (18-20nm), iyo inogona kungonangwa zvishoma mubundu microenvironment ine vascular disorders.Neiyi nzira, mushonga uyu unokwanisa kuramba uri mune bundu tishu, zvichikonzera kuwanda kwayo mubundu tishu uye kudzika kwakadzika munyama yakajairwa.Paunenge uchivandudza kushanda, chiitiko chemigumisiro chinowedzera kuderedzwa.
Kushandiswa kwepaclitaxel polymer micelles muChina
Muna Gumiguru 2021, China National Drug Administration (NMPA) yakazivisa kuti yekutanga paclitaxel polymer micelle muChina yakanga yatenderwa, uye chiratidzo chaive chisiri chegomarara remapapu.
Ongorora: Iko kugona kushanda uye mashandisirwo akaunzwa muchinyorwa chino zvese zvinobva kumabhuku akadhindwa.
Yunnan Hande Biotechnology Co., Ltd yanga iri nyanzvi mukugadzirwa kwepaclitaxel APIkweanopfuura makore makumi maviri, uye ndeimwe yepasi rose yakazvimiririra inogadzira paclitaxel API, inotorwa nechirimwa anti-cancer mushonga, yakatenderwa neUS FDA, European EDQM, Australian TGA, Chinese CFDA, India, Japan uye mamwe masangano anodzora nyika. .Hande inogona kupa kwete chete yepamusoro-mhandopaclitaxel mbishi zvinhu, asiwo tekinoroji yekusimudzira masevhisi ane hukama ne paclitaxel kuumbwa.Kuti uwane rumwe ruzivo, ndapota inzwa wakasununguka kutibata pa18187887160.
Nguva yekutumira: Zvita-15-2022