Paclitaxel, inozivikanwawo se red paclitaxel, tamsulosin, violet, uye tesu, ndiyo yakanyanya kunaka anti-gomarara mushonga wakawanikwa kusvika pari zvino, uye wakashandiswa zvakanyanya mukurapa kenza yemazamu, kenza yeovarian, uye mamwe magomarara emusoro nemutsipa uye kenza yemapapu.As a classical chemotherapy drug, zita repaclitaxelzvinotendwa kuti vanhu vakawanda vakazvinzwa.Ngatitarisei kusiyana kwemhando ina dzepaclitaxel munyaya inotevera.
Musiyano pakati pemhando ina dzepaclitaxel
1, Paclitaxel: Inoshanda pane microtubule / microtubule protein system, inhibits microtubule depolymerization, inovhara sero kutenderera muG2 / M chikamu, inotungamira kune isina kujairika mitosis kana kusungwa, inodzivirira bundu cell kudzokorora, uye inoita kuti masero ekenza asakwanise kuramba achipatsanura uye kufa.
2, Docetaxel: Maitiro echiito akafanana neaya paclitaxel, asi ane hukama hwepamusoro kune microtubule inosunga saiti uye yakakwirira anti-cancer chiitiko.
3, Liposomal paclitaxel: The mechanism of action yakafanana neye paclitaxel.Maposomes anoumbwa ne lecithin, cholesterol, threonine nezvimwe zvinhu zvakafanana ne phospholipid bilayer chimiro che cell membranes encapsulate paclitaxel, iyo inogona kuvandudza kunyungudika kwemvura, kupinda nyore nyore. kupinda bundu matishu kubva mutsinga dzeropa, uye kuderedza huturu hwemoyo neitsvo, nezvimwe.
4.Albumin-bound paclitaxel:hydrophobic paclitaxel inosanganiswa ne human serum albumin carrier by nanotechnology.Albumin inogona kuwedzera kukwira kwepaclitaxel mubundu nekusunga kugp60 receptor uye kuwedzera kuwanda kwepaclitaxel mu tumor tissue,saka ichiwedzera anti-tumor effect. .
Ose paclitaxel,doxorubicin,paclitaxel liposome kana albumin paclitaxel imhando imwe chete yemishonga yekurapa chemotherapeutic,uye ese ari eboka repaclitaxel muchikamu chemishonga yekurapa chemotherapeutic.Imhando imwe chete yemushonga.Paclitaxel mushonga wekurwisa tumor une musimboti wemicrotubule inhibitor, iyo inoshandiswa zvakanyanya mukenza yemazamu chemotherapy.
Ongorora: Iko kugona kushanda uye mashandisirwo akafukidzwa mumharidzo iyi anobva mumabhuku akadhindwa.
Kuwedzera kuverenga:Yunnan Hande Biotechnology Co., Ltd yanga yakatarisana nekugadzirwa kwepaclitaxel kwemakore makumi maviri nemasere.Ndiyo yekutanga yakazvimirira kugadzira pasi rose-yakagadzirwa anticancer drug paclitaxel iyo yakatenderwa neUS FDA, European EDQM, Australian TGA, China CFDA, India, Japan nemamwe masangano anodzora nyika.enterprise.Kana uchida kutengaPurogiramu inonzi Paclitaxel, ndapota taura nesu paIndaneti.
Nguva yekutumira: Oct-08-2022