Glabridin inotangira pachirimwa Glycyrrhiza glabra, inongowanikwa mumudzi nedzinde reGlycyrrhiza glabra(Eurasia), uye ndiyo huru Isoflavone chikamu cheGlycyrrhiza glabra.Glabridinine whitening, antioxidant, anti-inflammatory and other effects.Nekuda kwezvishoma zvishoma zve glabridin uye kuoma kwekunatsa nzira, ine zita rekuti "whitening gold".
1, Iyo yekuchena musimboti weGlabridin
Tisati tanzwisisa mutemo wekuchena we glabridin, tinoda kutanga tanzwisisa muchidimbu zvikonzero zvekugadzirwa kwe melanin.
Iyo synthesis ye melanin inoda zvinhu zvitatu zvakakosha:
Tyrosine:Chinhu chikuru chekugadzira melanin.
Tyrosinase: chiyero chikuru chinomisa enzyme inoshandura tyrosine kuita melanin.
Reactive okisijeni mhando: Tyrosine inofanira kusanganiswa neokisijeni mukugadzira melanin pasi pekuita kweTyrosinase.
Tyrosinase inogona kubudisa melanin nguva dzose.Kukurudzira kwekunze (kusanganisira zvakajairika ultraviolet mwaranzi, kuzvimba, allergies, nezvimwewo) zvinogona kutungamirira ku secretion yakawandisa, zvichiita kuti kusviba.
Panguva imwecheteyo, reactive oxygen species (ROS) inokonzerwa neultraviolet mwaranzi inogona kukanganisa phospholipid membrane yeganda reganda, rinoratidzwa se erythema uye pigmentation paganda. Naizvozvo, ROS chinhu chinogona kukonzera pigmentation paganda. Naizvozvo, inhibiting chizvarwa chayo chinogona kutadzisa chizvarwa che melanin uye pigmentation.
2, Kuchena kwakanakira kweGlabridin
Muchidimbu, maitiro ekuchena uye kupenya kwemavara inzira yekurwisa Tyrosinase uye reactive oxygen marudzi.
Glabridin inonyanya kuvharidzira chiitiko cheTyrosinase kuburikidza nemakwikwi ekuvharisa pabonde, kutora chikamu cheTyrosinase kure neinokonzeresa mhete ye melanin synthesis, kudzivirira musanganiswa we substrate neTyrosinase, nekudaro ichivharira synthesis ye melanin.glabridinpachayo ine yakanaka antioxidant uye anti-inflammatory effects.
Kupedzisa,glabridinkunyanya inhibits melanogenesis kuburikidza nemativi matatu: inhibiting basa reTyrosinase, inhibiting chizvarwa che reactive oxygen marudzi, uye inhibiting kuzvimba.
Ongororo dzakaratidza kuti inokurumidza, inoshanda, uye yakasvibira chena uye mafinya anobvisa cosmetic additive.Pane data rekuyedza rinoratidza kuti kuchena kweGlabridin kwakapetwa ka232 kune yakajairika vhitamini C, 16 yakakwira kupfuura hydroquinone(quinone), uye 1164 nguva iyo ye "arbutin".
Tsanangudzo:Kugona kuita uye mashandisirwo ataurwa muchinyorwa chino zvese zvinobva mumabhuku anowanikwa pachena.
Nguva yekutumira: Jun-28-2023