Tekinoroji Yekuchinjisa Sevhisi kune Yakajairika Paclitaxel Magadzirirwo

Tsanangudzo Pfupi:

Paclitaxel mushonga unorwisa bundu unoshandiswa zvakanyanya.Ijekiseni repaclitaxel rinoshandiswa mukiriniki rinoshandisa polyoxyethylene castor mafuta sesolubilizer, asi chiitiko chekusagadzikana kwakanyanya panguva yekushandiswa kwekiriniki, saka murwere anofanirwa kurapwa anti allergic asati atanga, Kuitira kubvisa kusakanganiswa kunokonzerwa ne polyoxyethyl castor oil, kukunda kukanganisa kwegadziriro iripo, uye kuwedzera kunyungudika nekugadzikana kwepaclitaxel,Albumin-bound paclitaxel yakatanga.Hande Biotech inopa Technology Transfer Service yeConventional Paclitaxel Formulations.Kuti uwane rumwe ruzivo, tapota bvunza online.

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Paclitaxel

Yakasikwa yechipiri metabolite yakaparadzaniswa uye yakacheneswa kubva pamakwati, matavi uye mashizha eiyo gymnospermous taxus chinensis inogona kukurudzira microtubule polymerization uye kudzikamisa iyo polymerized microtubules.Masero akafumurwa paclitaxel anounganidza huwandu hukuru hwemamicrotubules mumasero.Kuunganidzwa kwemamicrotubules aya kunovhiringa mabasa akasiyana-siyana emasero, kunyanya kumisa kupatsanurwa kwesero padanho remitotic, uye kunovharira kupatsanurwa kwesero kwakajairika.

Parizvino, inonyanya kushandiswa paclitaxel ndeye anticancer jekiseni uye zvigadzirwa zvekurapa (kusanganisira stents nemabharumu).Nekukurumidza kukura kwebiotechnology uye tekinoroji yekurapa, kushandiswa kwepaclitaxel kunogara kuchiongororwa, uye mamiriro akasiyana evarwere anoramba achivandudzwa.Tenda kuti munguva pfupi iri kutevera, ichave yakachengeteka uye inobatsira kurapwa kwevanachiremba nevarwere, uye kuchave nekuwanda uye kwakawanda mhando dzemishonga yeanticancer ine paclitaxel ine yakasimba anticancer effect.

Kufambira mberi kweprojekiti

Chidzidzo chepreclinical chapedzwa uye nzira yekugadzirira yakura.